A petroleum refinery model, Petroleum Refinery Life-cycle Inventory Mannequin (PRELIM), which quantifies vitality use and greenhouse gasoline (GHG) emissions with the detail and transparency adequate to tell policy analysis is developed. PRELIM improves on prior models by representing a more complete vary of crude oil quality and refinery configuration, utilizing publicly available information, and supported by refinery working knowledge and experts input. The potential use of PRELIM is demonstrated via a situation evaluation to explore the implications of processing crudes of various qualities, with a deal with oil sands merchandise, in different refinery configurations. The variability in GHG emissions estimates ensuing from all circumstances considered in the mannequin application exhibits variations of up to 14 g CO2eq/MJ of crude, or as much as 11 g CO2eq/MJ of gasoline and 19 g CO2eq/MJ of diesel (the margin of deviation within the emissions estimates is roughly 10%). This variability is comparable to the magnitude of upstream emissions and due to this fact has implications for each policy and mitigation of GHG emissions.